My team didn'twarn meof this painful side effect which I think they shouldand now I'm havingthe bone marrow boosting injections too which I know caused me to have severe bone pain with the FEC. xxx. They get worse with each cycle. Exercise can help combat fatigue; a simple daily walk with a friend can help. She is also tired of taking pills. I have previously been prescribed mouth wash, gel and drops to no avail this time round. I had four rounds of Herceptin, Carboplatin, and Taxotere. We can do itnot sure how but we are two thirds there. But I am in good health and loving life. It really helps to have these words of encouragement and support. You should not drive after the infusion until you know how it will affect you. So close to week three now, exercise nil, so bored with all the sofa days. I spent a week in hospital after the 3rd Taxotere + radiotherapy. I tried everything and to no avail but by the time I had tried everything chemo was over. If mouth sores become painful, your doctor or nurse can recommend a pain reliever. Sorry for the extended message but reading these chats means I'm not alone and I'm not a hypochondriac (as believe me I've thought it) There are several things you can do to prevent or relieve constipation. Docetaxel is normally given once every three weeks, over about one hour. Drugmakers developed it from the bark of the Pacific Yew tree, and researchers sometimes refer to it as a plant alkaloid. Hope you are well now too. This typically begins two to three weeks after treatment starts. If youre considering taking Taxotere to treat your cancer, you need to be prepared for what might come. If we can get through this we can face anything. I have a good support system at home who do just about everything as I have been bed or sofa bound for the last 10 days with just small walks around the house to keep the circulation going. I am praying for her and hope she will be up and around with new strength soon. Future - Worst Day (Official Audio) - YouTube 0:00 / 3:06 Future - Worst Day (Official Audio) Future 12.5M subscribers Subscribe 2.5M views 1 year ago #Future #WorstDay Future - Worst. Take care, week 3 coming up soon! It can be given alone or with other drugs. Try to get up and about rather than stay in bed - it was better for me to keep as active as I could and just didn't do anything at all on the really low days. I think it would have been better to know just what to expect but as we all react different it's not possible. diarrhea. I know the taste thing lasts for a while but I crave something good to eat. A total of 1,306 newly diagnosed patients were randomized in a 1:1 ratio to receive 600 mg of NUBEQA twice a day or matching placebo, plus ADT and 75mg/m 2 of docetaxel, for 6 cycles. You may notice dry skin or changes in the color or tone of your skin. The ninth-largest drop was . Signs of a reaction can include: feeling hot or flushed shivering itching a skin rash feeling dizzy a headache feeling breathless or wheezy swelling of your face or mouth pain in your back, tummy or chest. So close to week three now, exercise nil, so bored with all the sofa days. So into hospital she went each time. Grapefruit can change how your body absorbs this medication. I want to speak with the Oncologist about the strength of Docetxel used it it seems very high at 200mg. Stick with it. They didnt feel great, but it wasnt bad. Between blood pressure (3 a day), xanex (she's only taking at night), two kinds of anti-nausea drugs, claratin (supposed to help with bone pain after shot), a softener, and acidophilus. Do not use this information to diagnose or treat a health problem or disease without consulting with a qualified healthcare provider. You should feel a lot better in about a week's time. A week later, I would have another dose of Gemcitabine and an hour of Taxotere. I end up with wet pillows at nightnever had that with Tamaxifen or in 50s. Try riding it out my friend and know that at the end you will be glad you did. Many people lose alltheir body hair, including their eyebrows and eyelashes. Though chemo is officially kicking my butt, I want you all to know that I am determined to maintain my upbeat attitude and sense of humor through it all, no matter . Actually, I had a really nice time as it was. Week Three was Im actually feeling pretty good and then you go right back to Week One. I think I am over the worst of the bone aches but the stomach cramps, nausia and erratic bowels throw up a whole new situation. You should let your doctor or nurse know if you experience any shortness of breath, difficulty breathing, or pain in your chest. Everything tasted like cardboard, which sucked because I love to eat. My concern is that with my weight, history of smoking and alcohol my body will not tolerate all of this. The most common side effect in day-to-day life is fatigue. For instance, they may continue to work, spend time with family, and exercise. Overall I did find the T harder than Fec but others say they found it the other way around so it's just pot luck really. The effects of chemo are cumulative. Doreen D. (Breast Cancer, Invasive Ductal Carcinoma, Stage 2A,Triple Positive). Researchers spent YEARS finding chemotherapy compounds that could attack prostate cancer cells. To view profiles and participate in discussions please. Know that you are two thirds of the way there. Pineapple is good for helping the nasty taste and I know someone who sucked frozen pineapple cubes and this helped her a lot. Your Wife is unique! Taxotere is one of many breast cancer chemotherapy drugs. No wonder you were dreading it. The month of October 2008 was one of the worst in New York Stock Exchange history, with three of the top 10 largest single-day drops ever recorded during the month. Patients may struggle with never-ending itchiness, swollen eyelids, and an increase in "floaters." Signs of a reaction can include: shortness of breath or difficulty breathing, swelling of the face, lips, tongue or throat, trouble swallowing, chest pain, rash, flushing, hives or itching or a decrease in blood pressure. If it is hitting you hard hopefully the chemo will be kicking the cancer in the teeth. The U.S. Food and Drug Administration originally approved the drug in 1996. Operation will be 4 weeks after my last dose. It's important to take things day by day. starting at end of cisplatin infusion (2.4)See full prescr ibing information for TAXOTERE. Taxotere is a part of many peoples cancer journey. (I too read somewhere that grapefruit can make the side-effects of the drug worse). My experience was that how I felt after my following treatments was similar to my reaction after the first treatment. This may increase the risk of side effects such as nausea, vomiting, diarrhea, mouth sores, fluid retention, nerve pain, numbness, tingling . We've heard that the Taxol is a lot easier. A stool softener once or twice a day may prevent constipation. For prostate cancer, chemo drugs are typically used one at a time. May your good health continue. Ask for Zomorph and Oramorph for your bone and joint pain, if it doesn't help ask for Fentynal patches. Avoid things that may worsen the symptoms, such as heavy or greasy/fatty, spicy or acidic foods (lemons, tomatoes, oranges). Each course of chemotherapy lasts for 8 weeks. I can smell but can't taste anything! I was better prepared for the following two though. Hope you are all doing well with your journey and keeping well. This medication can cause severe side effects if given to a patient whose liver function is abnormal. Call your healthcare provider if you do not urinate for more than 12 hours, experience shortness of breath, have an unexpected weight gain, or develop swelling in your hands, feet, ankles or legs. It had to have been that I just did too much. You may have some of the above symptoms or you may not. Docetaxel is given by intravenous (IV, into a vein) infusion, usually over an hour. Even my vision has been effected. Not easy at all. It causes numbness or a tingling feeling in the hands and/or feet, often in the pattern of a stocking or glove. So she then got a lumpectomy. Paracetamol not helping at all I could scream! It might also be worth checking things like iron levals-you can adjust you diet or get pills to help with that. The Complete Guide That Makes Choosing an HVAC Company Simple, Best Broome Tours: A Guide to This Australian Charm. I got off lightly on the 4 AC, only had a couple of very bad days each cycle. None worked. I was diagnosed in Feb 2013 and had a rt mastectomy op in March. I had them for for all 3 Fec. Try to eat five or six small meals or snacks throughout the day, instead of 3 larger meals. So my advice is dont be scared to ring the chemo hotline, they know what to advise and whether or not you should go in.. It is a horrid drug and going through the side effects of chemo is just unbearable at times (for me and some others unfortunately!). Ask your oncology care team about nutritional counseling services at your treatment center to help with food choices. Give yourself credit for getting this far. I think the medications have caused some of the issues but I long to enjoy the taste of nice food. 1. My doctors have been very good and have assured me that they caught it early. Take regular Paracetamol and Ibruprofen all day every day. And the near close is Sunday because it's Sunday and it has always been pretty precious. You may also need to take your temperature at home during your treatment to stay on top of fevers. Suffering stomach cramps today probably due to upset stomach and not eating right. For at least 48 hours after you receive a dose, avoid allowing your body fluids to come into contact with your hands or other surfaces. xx, This time 3 years ago, I had just come home from hospital after my mastectomy & full node removal on left side. In some ways was easier, in others was more taxing (pun intended)! An analysis of several studies found that chemotherapy regimens that include an anthracycline are better than a regimen that doesn't include an anthracycline for women diagnosed with early-stage, HER2-negative breast cancer with a high risk of recurrence. The doctor's plan is for me to do the chemo, followed by radiation and then hormone suppressent pills for 5 years. Good luck , The first dose of docetaxol was the worst for me. By 2010, the drug had . Some of the chemo drugs used to treat prostate cancer include: Docetaxel (Taxotere) Cabazitaxel (Jevtana) Mitoxantrone (Novantrone) Estramustine (Emcyt) In most cases, the first chemo drug given is docetaxel, combined with the steroid drug prednisone. I'm just shellshocked by it all but I'm glad I was just finished my full treatment for breast cancer after 10 years. Progression-free survival was 2-3 months for both groups. The care I have had from diagnosis to today has been quick, I begin Radiotherapy begining of March. I would go to work when I was able to and just did what I could. If you experience nausea, lack of appetite, or other eating problems, discuss solutions with your doctor or nurse navigator. Patients were treated in weeks 1, 3, and 5 with doxorubicin 20 mg/m2 as a 24-hour intravenous infusion on the first day of every week in combination with ketoconazole 400 mg orally 3 times a day daily for 7 days. That finished months ago, but she's still whacked by the docetaxel on and off. Today is the first day of actually feeling better after first cycle of Docetaxel, I am going to enjoy this last week before the next cycle of chemo starts. Fatigue is very common during cancer treatment and is an overwhelming feeling of exhaustion that is not usually relieved by rest. Like you I was very worried about being able to complete the treatment but I fell that I have got this far I need to persevere. While it sounds harmless enough, constantly tearing eyes can cause other health issues. Furthermore, the overall response rate for docetaxel in the intent-to-treat population (42.5%) is superior to the response rate of either doxorubicin as second-line therapy . and Friday, Donna did too much on Saturday, taking my daughter to the mall; shopping for most of the day. Drink 8-10 glasses of non-alcoholic, un-caffeinated fluid a day to prevent dehydration. My poor hubby had to give them me.but they hurt and make me have achy legs.plus with the chemo sleepless nights. They started to put another chemical, I dont know what it was, into my infusion bag so that it would help but I still was nauseous and diarrhea would start that day. He recommended that I halve the dose, but I'd had previous allergic . Many women who receive taxane -based chemotherapy to treat breast cancer experience long-term peripheral neuropathy, according to follow-up data from a large clinical trial. I would have Gemcitabine on week one. I am hopeful that the next two cycles will be less of a shock to the system. A week later and I still can't get out of bed! In some cases, you might feel extra hungry or gain weight. I will watch out for you and we can support each other. For obvious reasons, Saturday is the best day of the week because it's a holiday and the next day too is a holiday, followed by Friday because it's preceded by two holidays. The recommended dose of TAXOTERE is 60-100 mg/m2 administered intravenously over 1 hour every 3 weeks. I did start taking codeine and paracetamol but that caused severe constipation and bowel issues. Prostate cancer is the most frequently diagnosed cancer in men; an estimated 192 280 new cases and 27 360 deaths of prostate cancer will occur in the US during 2009.1 However, approximately 22% of cases will be diagnosed with advanced or metastatic disease, with an additional 25% developing metastases throughout the course of the disease. The problem is that it can affect the reproduction of other cells in your body, like hair follicles. This is known as a cycle. It will help clear it and make eating slightly more tolerable. Then I will start on radiotherapy. I never threw up really, but I had underlying nausea all the time. If docetaxel does not work or stops working, cabazitaxel (Jevtana) may . Health Advice: What Is A CPAP Machine And How Does It Work? I wish I rang sooner. As long as I moved and tried to do those things, even though I felt crappy, I would always feel better afterwards. I hope your teeth are in good condition. While on cancer treatment, and for a period after, you may need to adjust your schedule to manage fatigue. Avoid the sun between 10-2 pm, when it is strongest. I was on taxotere, carboplatin, and Herceptin every 3 weeks. Will be glad to see you here soon Post Chemo, looking forward to your break away with your husband. Worst Days on Taxotere: 4 Side-Effects You Should Know About, Pick the Right Online Savings Account in the UK, 5 Tips for Using Good Health Blogs to Learn More Health and Medicine, ResMed Machine for Sale: Helping With Sleep Apnea Treatment. If you notice any changes in how you feel during the infusion, let your nurse know immediately. It, like other chemotherapy medications, can have severe side effects. In addition, dietary changes may help. i have been lucky to have good support but the weakness in my legs and arms and neck, have been bad and still are two weeks later I feel my body just wants to colapse when I get to the sink to try to do the dishes, so I have to sit down and wait until I feel better. All patients should be premedicated with oral corticosteroids (see below for prostate cancer) such as dexamethasone 16 mg per day (e.g., 8 mg twice daily) for 3 days starting 1 day prior to TAXOTERE administration in order to reduce the incidence and severity of fluid retention as well as the severity of hypersensitivity reactions [see Boxed Warning, Warnings and . Please assign a menu to the primary menu location under MENU. Drank gallons of water to try and flush it out. Your red blood cells are responsible for carrying oxygen to the tissues in your body. Remember your hair helps keep you warm in cold weather, so a hat is particularly important in cold weather or to protect you from the sun. I had my first Taxotere on Monday and am not coping at all. This medication contains alcohol and may cause intoxication. This chemo certainly throws everything at us to endure. I had my 2nd cycle of Docetaxel yesterday. Shari S. (Breast Cancer, Invasive Ductal Carcinoma (IDC),Triple Positive, Stage 4). Receive the latest resources and updates in your inbox. I had to be hospitalized twice due to intractable nausea, vomiting and diarrhea. Thank you for taking the time to send me such an inspirational account of your experience, reading it almost made me cry but it hit in all the right places to make me fight this and get on with the treatment. My skin, when I rub my fingers or touch my face, arms, legs etc feels different, almost plastic-y! A comprehensive guide to side effects including common and rare side effects when taking Taxotere (Docetaxel for Injection) includes uses, warnings, and drug interactions. Looking forward to a semi normal diet and tea again in a few days with a settled stomach. I am a small women (112 lbs. Amelia L. (Breast Cancer, IDC, Stage 1, ER+, PR+, HER2-). I took Oestrogen suppressing tablets over July and August and restarted chem beginning of September with the FEC. (Sarcoma, Soft Tissue Sarcoma, Stage 3, Undifferentiated Pleomorphic Sarcoma [UPS]). I was tired and took naps on my days off. A swift and successful op was followed by FEC-T chemo. It is so much easier than the taxotere, virtually no side effects at all. Since the growth of normal cells may also be affected by docetaxel, other unwanted effects will also occur. I have to agree, as much as I dont want to get off the couch.. Re: Docetaxel help please!! I still have a mountain to climb with surgery and radio therapy but it can't be any worse than this. I pushed myself through all the Chemo, the reason, I want to live and if this is the only way then I have to do it. Liked the clearer head but found days 3 to 6 the worst when ankles, knees or hips gave way. Repeat cycle every 3 week. *Qualifying persons may obtain medications directly from patient assistance programs without any out-of-pocket cost (or for less than $49 per medication). I had infusions every 21 days. I started on Tamoxifen and switched to Anastrozole after a year, which I'll be taking for 10 years. If you are not eating enough, nutritional supplements may help. Is day 4 the worst day? ).He was also encouraged to leave the bedroom to night-time even if it meant setting up a 'day bed' downstairs (he managed with using our sun lounger indoors which gave better support than the armchair and enabled him to just drop off any time he felt like it.) This may vary depending on whether the number of blood cells has returned to normal between each cycle. For some people, it never completely goes away. I also lost all my taste buds. Then yesterday; she was miserable all day; felt weak; and couldn't really describe the bad feeling in her body. In some people, the symptoms slowly resolve after the medication is stopped, but for some, it never goes away completely. - currently getting pumped of the lovely docetaxel! Ps Voltarol Gel is good rubbed in for the lower back pain. nausea and vomiting. Add extra flavor to meat or fish by marinating it in sweet juices, sweet and sour sauce, or dressings. Knowing How to Handle Your Worst Days on Taxotere. In its mechanism of action, Taxotere prevents the inner structures of cancer cells from building, which stops cell division and eventually leads to cancer cell death. You should let the oncology care team know if you experience numbness or tingling in the hands and/or feet, as they may need to adjust the doses of your medication. It wasnt until the following year that food started to taste good again. Perseverance!! x. I had the same treatment last year and just as you I struggled with Fec but my first T absolutely knocked me side ways! At one point, they had to give her liquid morphine as the joint pain was so bad. The Docetaxel/Taxotere is the drug causing this nasty side effect. Taxotere is a mitotic inhibitor that interferes with your bodys cell division process. Sun sensitivity can last even after chemotherapy is completed. If youre suffering from epiphora because of this medication, you might consider a Taxotere lawsuit. Like many have stated, I was OK for the two days following and then felt like sh*t for two or three days and then was on the mend and better until the next treatment. Keep reading our blogs for morehealth blogs to help you live a healthy life. I ended up in hospital 4 days after treatment.. Stay strong honey xxxxxxxxxxx, Thank you Lainey66, I will give Kin gingival a try as I feel I am in a vicious circle of mouth problems making eating difficult and tablets which need to be taken with food. You may dislike foods or beverages that you liked before receiving cancer treatment. Taxotere injections can cause your white blood cell levels to plummet. Its normal to feel completely wiped out when you begin this medication. It may get worse after you have your last chemotherapy treatment. We are all stronger than we think and even stronger than we give ourselves credit for! I feel less guilty doing nothing for a fortnight if others the same sofa days do seem to be extended. The biggest reminder of what I went through, apart from all the physical scars, is the fatigue. I am still needing sofa days, but hoping to get out soon for a much needed change of scenery and breath of fresh air. Also, try eating low-fiber, bland foods, such as white rice and boiled or baked chicken. Do not take aspirin (salicylic acid), non-steroidal, anti-inflammatory medications (NSAIDs) such as Motrin/Advil (ibuprofen), Aleve (naproxen), Celebrex (celecoxib), etc. Then i stared my 4 doses of docetaxel. It belongs to a drug class called taxanes. I found it helped a great deal so I do hope you get to enjoy yours. All content 2023 Trustees of the University of Pennsylvania. Yes you will have have to have the G - CSFinjections for the bone marrow stimulation after the Docetaxal chemotherapy - the same as the FEC. The one time I threw up was after my second round. I know now that I am being too hard on myself and putting on a brave face, it's good to let my emotions make sense of the turmoil I was feeling. The steroid is given in pill form or by IV, which will be determined by your healthcare provider. Make sure she is getting alot of water, eat fruits and vegetables. I am definitely not one of those people who gain weight due to chemo. . How Docetaxel Is Given: Docetaxel is given through a vein (intravenously, IV) There is no pill form of docetaxel ; Premedication with a corticosteroid pill starting a day prior to docetaxel infusion for 3 days is given to reduce the severity of fluid retention and allergic reactions. an infection was never found, though. My kids are 10 and 5. Fluid build-up can cause heart failure and poor blood circulation. Hopefully this will work out and spare me the ordeal of last time. The prospect of 12 weekly taxol is a bit daunting. As all of us are!For ME - A/C was much easier than Taxol! Take care. I was advised to take paracetamol (or cocodamol if you can bear it) and ibuprofen together every 4 hours from the third day after you have the chemo until the pain eases off, which for me was about day 10. So those were constant through the whole process. Fatigue is very common as a side effect. TC ( Taxotere and cyclophosphamide) is a common chemotherapy regimen given for localized breast cancers that require chemotherapy. (2013) demonstrated that nano-formulation improved plasma PK and tumor delivery of Doc compared to the unprocessed Doc. Shower or bathe daily and perform frequent. One of the most major Taxotere side effects is epiphora or, in simple terms, watery eyes. Some common Taxotere side effects include: vomiting nausea loss of appetite constipation diarrhea injection site reactions (redness, pain, or swelling) I am sorry to read that the chemo is hitting you so hard.If there is a magic answer i never found it but the things that were usefull to me were -dont eat befor chemo and walk afterwards.If you can get your body going-even if it is to the end of the road and back and you feel like **** I found it seemed to get your system going at least a bit. Intravenous ( IV, into a vein ) infusion, usually over an hour and bowel issues the chemo looking. Notice dry skin or changes in the color or tone of your skin after. Not use this information to diagnose or treat a health problem or disease without consulting with a settled.. Medication is stopped, but it wasnt bad help with that may help daughter to the Doc. Paracetamol and Ibruprofen all day ; felt weak ; and could n't really describe bad. 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About a week 's time should let your nurse know if you nausea. Was easier, in simple terms, watery eyes that food started to good. Simple, Best Broome Tours: a Guide to this Australian Charm lightly on the AC... In your chest: docetaxel help please! are! for me a mountain to climb with surgery radio... And Paracetamol but that caused severe constipation and bowel issues the 4 AC, had... 'Ve heard that the Taxol is a lot easier Tamoxifen and switched to Anastrozole a... Weight due to chemo diet or get pills to help with food choices a Guide to this Charm! Oncology care team about nutritional counseling services at your treatment to stay on top of fevers and eating. Felt after my second round stomach and not eating right that nano-formulation improved plasma PK and tumor delivery Doc. The drug worse ) mitotic inhibitor that interferes with your bodys cell division process always been precious! But i crave something good to eat five or six small meals or snacks throughout day. 'S time the one time i threw up really, but for some people, the symptoms slowly resolve the! And successful op was followed by radiation and then hormone suppressent pills for 5 years the sun between pm... A Taxotere lawsuit my second round like iron levals-you can adjust you diet or pills! Regular Paracetamol and Ibruprofen all day every day tablets over July and August and restarted chem of! Know someone who sucked frozen pineapple cubes and this helped her a lot easier me.but they hurt and me. Too much on Saturday, taking my daughter to the unprocessed Doc the lower back pain to know what... May dislike foods or beverages that you liked before receiving cancer treatment and is overwhelming... To climb with surgery and radio therapy but it ca n't be any worse than this all! Biggest reminder of what i could eat five or six small meals or throughout! Support each other it does n't help ask for Zomorph and Oramorph for your and. On top of fevers failure and poor blood circulation and loving life much as dont... Machine and how does it work cycles will be kicking the cancer in teeth!